Microarray Substrates

The quality of the glass substrate surface modification is always a critical issue in microarray analysis. As CapitalBio, the slide surface modification process has been optimized for uniformity and compatibility with a number of reactive groups. 
CapitalBio offers a full set of precision modified glass slides, for both contact and non-contact printing of various nuclear acids and proteins.

OPAminoSlide

AminoSlide contains amino groups, which can be used for attachment of nucleic acids, esp. long (>70 mer) oligonucleotides and PCR products. The electrostatic interaction between the positively charged amino groups on the surface and the negatively charged nucleotide chains are strengthened after heating or UV crosslinking treatment. The surface wettability is slightly adjustable to meet different requirements for spot diameters. Low background fluorescence, high surface coating homogeneity and good spot morphology make it an excellent substrate for gene expression analysis and SNP microarray tests.

OPAldehydeSlide

AldehydeSlide contains aldehyde groups for covalent binding of amine-modified nucleotides, esp. short amine-modified oligonucleotides. No heating or UV crosslinking treatment is required for immobilization for AldehydeSlide, which make it easier to use.

OPEpoxySlide

EpoxySlide contains epoxy groups, which has been proved to have good reactivity to primary amine-containing peptides and protein molecules. The surface wettability is slightly adjustable to meet different requirements for spot diameters.

OPAmino/Aldehyde/EpoxySlide

OPPolymerSlide

PolySlide has a thin polysaccharide surface of layer, which enables excellent spot morphologies and consistent spot sizes. Due to the porous nature of the 3D polymeric coating layer with abundant activated covalent binding sites, PolySlide is superior for maintaining protein activity and is suitable for protein microarray construction.

	OPPolymerSlide G
	OPPolymerSlide H
	OPPolymerSlide A/C/D

Company Info:

Headquartered in Beijing, China, CapitalBio is a leading life science Company that develops and commercializes total health-care solutions including a broad range of innovative biochip-related products for genomic, proteomic and cellomic research, bio-safety testing, clinical applications and to address wider human health needs. CapitalBio warmly encourages discussion of new business, marketing and production opportunities, etc. Both through innovation and a commitment to rapid product development, 

CapitalBio is seeking to reduce the cost of products, to benefit our customers.

For further information and detailed budget, send us an email to technicalsupport@biotools.eu >>

Specific Characteristics

Manufacturing and Quality Control

Each step of slide surface modification is under stringent control in a state-of-the-art clean-room. Slide products undergo rigid quality control inspections, including contact angle measurement to monitor surface wetting characteristics, background scanning for coating homogenity and standard experiments for immobilization and hybridization/immunoreaction ability testing.

• General Characteristics